Brand Names

Focalin, Focalin XR 

What is dexmethylphenidate used for? 

Dexmethylphenidate is in a class of medications called “stimulants” that are used for attention-deficit/hyperactivity disorder (ADHD).

How is dexmethylphenidate different from methylphenidate? 

Dexmethylphenidate is a more active formulation of methylphenidate. 

What are the most common side effects seen with dexmethylphenidate? 

• Decreased appetite 

• Nausea

• Dry mouth 

• Anxiety

• Headache 

• Insomnia 

• Jitteriness 

Contraindications

• Dexmethylphenidate should not be taken if your child has had an anaphylactic reaction (hives or swelling of the tongue) to dexmethylphenidate previously. 

• Dexmethylphenidate should not be taken if your child is currently taking or has taken a medication in a drug class called monoamine oxidase inhibitors within 14 days. Monoamine oxidase inhibitors include: 

  • Isocarboxazid

  • Phenelzine 

  • Selegiline 

  • Tranylcypromine 

  • Moclobemide

Tips & Tricks to administer methylphenidate

If your child is having difficulty taking dexmethylphenidate (capsules or tablets), it can be mixed in some foods or beverages. Please keep in mind that if a medication is mixed with food or drink, it should be taken immediately. The mixture should not be saved or consumed later.

• Dexmethylphenidate immediate release tablets can be mixed with any food or drink of the child’s preference.

• Dexmethylphenidate extended release capsules should not be chewed, crushed or divided. The capsule can be opened and sprinkled over a spoonful of applesauce. 

Breast feeding considerations 

• Dexmethylphenidate can be present in breast milk if being taken by the mother. 

• Although the levels of methylphenidate are typically low in the infant compared to the dose taken by the mother, the risk vs. benefits should be discussed with your child’s physician. 

• The breastfed child should be observed for side effects of stimulant medications such as decreased appetite, insomnia, nausea and fever. 

Storage Considerations 

Almost all ADHD medications have a high potential of abuse and misuse which can lead to addiction. Due to this risk, the Drug Enforcement Agency (DEA) has classified these medications as a controlled substance (C-II). In order to dispense these medications, pharmacies must follow a strict set of rules and regulations set by the DEA. 

At home, these medications should be stored in a safe location that cannot be easily found and accessed by guests, visitors or other family members.

The information in this database regarding prescription drugs is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interaction or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate, or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. See disclaimer.