Brand Names

Vyvanse

What is lisdexamfetamine used for? 

Lisdexamfetamine is in a class of medications called “stimulants” that are used for attention-deficit/hyperactivity disorder (ADHD). 

What is the difference between lisdexamfetamine and dextroamphetamine? 

When lisdexamfetamine is taken it is rapidly absorbed and is converted into dextroamphetamine by the body. 

What are the most common side effects seen with lisdextroamphetamine? 

• Decreased appetite 

• Upper abdominal pain 

• Dry mouth 

• Insomnia (trouble sleeping)

Contraindications

• Lisdexamfetamine should not be taken if your child has had an anaphylactic reaction (hives or swelling of the tongue) to lisdexamfetamine, dextroamphetamine or amphetamine previously. 

• Lisdexamfetamine should not be taken if your child is currently taking or has taken a medication in a drug class called monoamine oxidase inhibitors within 14 days. Monoamine oxidase inhibitors include: 

  • Isocarboxazid

  • Phenelzine 

  • Selegiline 

  • Tranylcypromine 

  • Moclobemide

  • Linezolid

  • Methylene Blue 

Tips & Tricks to administer lisdexamfetamine

If your child is having difficulty taking lisdexamfetamine (chewable tablets or capsules), it can be mixed in some foods. Please keep in mind that if a medication is mixed with food or drink, it should be taken immediately. The mixture should not be saved or consumed later.

• Capsules

  • Capsules should be swallowed whole. Do not chew. 

  • Capsule can be opened and entire contents should be mixed thoroughly with yogurt, water or orange juice.If the powder within the capsule is compacted and difficult to empty, use a spoon to help break apart the powder. 

• Chewable tablets 

  • Chewable tablets should be chewed throughout before swallowing and can be taken with any food or drink. 

Breast feeding considerations 

• Lisdexamfetamine is concentrated in breast milk if being taken by the mother. 

• Per the American Academy of Pediatrics (AAP), dextroamphetamine and amphetamine is contraindicated during breastfeeding. 

Storage Considerations 

Almost all ADHD medications have a high potential of abuse and misuse which can lead to addiction. Due to this risk, the Drug Enforcement Agency (DEA) has classified these medications as a controlled substance (C-II). In order to dispense these medications, pharmacies must follow a strict set of rules and regulations set by the DEA. 

At home, these medications should be stored in a safe location that cannot be easily found and accessed by guests, visitors or other family members.

The information in this database regarding prescription drugs is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interaction or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate, or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. See disclaimer.